Can loan-pay-down outweigh negative cash-flow???

[Cam Jimmy]

I was just curious about peoples thoughts on this. In super high cost areas like San Fran, NY City, etc.. Is there ever a time when it's OK to cash-flow negatively, as long as your loan pay-down out weighs that??  For example: you are -$200/mo in cash flow, but your loan-pay-down is $6,000/yr+ ($500/mo+). This makes sense to me, but I'm sure people out there would never do this.... AND GO!!