Send letter to out of st. owner who is in commercial real estate?

[Hen Ley]

I live in a resort town with many out of state owners.  Occasionally I drive by a property and, because it looks like it has some deferred maintenance, I'll consider selling the owner a letter expressing interest to purchase.  Given it's small town, I typically do preliminary online search-  Sometimes I find that the owner is actually in real estate, but in a different state where they live, and also potentially not specifically in residential real estate.

Is it worth sending a note to these types of owners or better to avoid?