Tips and formulas for investing.

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I am pretty much just starting out. I am confident in my ability to figure out if I will make money or not. I have a realestate book that gives the line items to consider. Is there a quick way to see if somthing is a deal or not with out going through all the numbers? I hear you guys talk about the 2% rule. Is there any quick checks that I could do before putting a lot of time and effort into a deal? Also when you invest for flips is there a % of the sale price that you expect to pocket? like say 20-30% of the selling price is gross profits or net profits?