Pros & Cons for Rentals on Main Roads?

[Nader Hachem]

Looking at a few properties, i've run into situations where these properties are on main roads such as 5 Mile, 7 Mile (Metro Detroit), etc.. 

What are the pros and cons of having houses on main roads? Are these something to avoid? Harder to rent out? Just thinking from the renter's perspective, I'd hate to live on a main road... difficulties of parking, difficulties backing in and out of drive-way, noisy.. but i may be missing something

thoughts?