How best to respond to unsolicited offers to buy my home?

[Victoria Stone]

Hi there, 

I'm not a real estate professional and, in fact, have no experience selling RE.  I am, however, interested in perhaps selling my primary residence, for the right price ;), and have received some letters from RE agents saying they have clients who are interested in the house as it's in an area with low inventory.  I understand some of these REs may simply be trying to drum up business, so what's the best way to respond to find out if a) this interest is legitimate - i.e. there are actually buyers who are interested and this isn't some bait and switch tactic, and b) if the buyers are indeed real, how to get the best deal for my property if I decide to proceed. 

Any advice about handling this situation would be greatly appreciated.  Thank you!