Can a spouse quit claim a property right before selling?

[Mark Nickelson]

Hello BP Nation! 

I am working on a deal where the husband and wife owner/sellers are separated but not divorced, the wife says her husband is on board and will sign the papers but won't let me speak with him which has me a little concerned he may go sideways between now and closing. (I'm pretty sure he has a substance abuse issue)

If he were to quit claim the house to her so she had 100% ownership would that raise any red flags with the title or potentially interfere with my deal when we go to close?

The house is not a personal residence and is owned free and clear. FYI..

Thanks in advance!

Mark