2% rule in Southern California

[Madison Balter]

How does the 2% rule work in Southern California? A house in a C+ neighborhood can cost $450K for roughly 2400 sq feet. That would mean rent would should cost $9k/month.... Is this a bad neighborhood to invest in, or is there another rule out there for these types of areas?  Also if you use the 50% rule the house should only be worth $130k.