I think refinancing would be a better option.

On the other hand, if you have a lower budget, let’s say $100-$150k.

Both have the Roth option.  401k has Roth built in, SDIRA is either pre-tax or Roth.   

Alternatively, I could hope that my next assignment will be in a better market with more options, maybe lower rates, and more cash on hand.Should I accept that no market is perfect and get in the game now, or hold out for a year to enter a potentially better market with more capital to invest?

On the other hand, if you have a lower budget, let’s say $100-$150k.

Quote from @William Coet: Hello,Trying to get a ballpark on what the current best terms and lenders are for 6 unit multi-family.Lowest origination fees, Lowest APR.Thanks If you go the Multifamily DSCR Loan route (instead of more traditional bank financing) rates probably anywhere from 8-10%, however, monthly debt service tempered by 30-year am and 10-year IO options 

I know med students are always looking for apartments.Best options in lewisburg are probably student housing, scrape-and-build, new multifamily, or flips.Tim

-Homes that aren't falling apart/need major rehab on the property-Prices in six figures overall not seven figuresWhat 2-3 cities should I really pinpoint in terms of the Zillow map to get an idea of some great options?

Considering the option of tear down and build a new house, I was wandering if there's an average percentage difference in insuring a new home vs an older house?  

Maybe instead what you could do is focus on building a big enough reserve while you are living there then lower those numbers a little bit when you move out.