As far as a second/vacation home and STR would you consider MTR to travel nurses/business people?  

Likely causing the rate increases This depends on the lender.

I operate another business out of the ground floor storefront.

A trust may offer some of the same benefits as an LLC, depending on your goals, and allowing you to claim the part of the house you live in as homesteaded tax.Make sure you have the right home insurance and consider an umbrella policy for extra protection.Certainly buying a house, using conventional financing with limited money down as a primary residence and renting out parts of the house to help pay the mortgage, is a smart financial move.

You are looking to rent or buy a space with a partner to have a personal fitness business or just a class?

As a matter of fact, I had a discussion with a flipper a few weeks ago that brought this new reg to my attention, he was considering getting out of the business realizing that now he would have to comply, and that it would substantially hurt his bottom line.For me, as a conservative leader, I see it as a positive.

They were referred to me by a friend of mine who owns the a large local business.

Totally depends on the deal.

Or, find a business partner who has money, but not time. 

We are still involved in the business, but way way less.