However, my wife and I are both in the medical field and have quit a bit of debt due to school loans and mortgage therefore our net worth is currently in the toilet (although loans/mortgage at low rates). 

.- a medical center (a plus).- a market (a plus).- high rent to own ratio (a plus).Based on this information —as it aligns to my personal ideals— I’d only be interested in Old Fourth Ward and possibly Hapeville as potential neighborhoods. 

We were renting out our house, living in the in-laws’ basement, experiencing medical and other hardships, and had $65K of debt (medical, consumer, vehicle, college, etc.).

The narrative will flip when Detroit shows population growth for the first time in 70 years.If you get your information from mainstream media, you are always 2-3 years behind the times.

Those just aren't great set ups, particularly for traveling medical professionals how work long hours and need quiet when they're not working. 

If it were me, I would want to know what the debt is for; medical, student loans, alimony/child support payments, shopping sprees.

I contribute 6% to my 401k (with a 4% company match) and all medical/benefits are fully covered by my employer. 

Demand has historically been high for travel with the theme parks, weekly military basic training graduations, medical district, and historic downtown draw (Alamo, Riverwalk, etc).

Furthermore, your E-4 really has a lot more take home pay because they don't have to pay for medical benefits, retirement, life insurance, etc. and much of their compensation (think Basic Allowance for Housing or BA for Sustenance) isn't classified as "pay" and therefore it's not taxed.

@Angelo Mart That is actually really interesting you would say that because I've been finding that area more and more attractive in terms of buying rental properties for students given its close proximity to the law school / medical school / NJIT.