By major I mean there is a lot of traffic, but it's still only two lanes.

If you can move outside of the 7-9:30 am and 3:30 to 6:30 windows then traffic is much less of an issue.

I am concerned about renting this property and having tenants complain frequently about heavy traffic, kids in the yard, etc.

A quite neighborhood at 12:00 noon might be a rowdy neighborhood with obvious drug traffic after dark.You say 2-3 streets away is mostly occupied.

The problem: it's a 4.5 hour drive (+/- 1 hr depending on traffic).What route would you guys take?

The bank and the building owner may not want a big billboard right there, but if the city ordinance allows it, and the traffic count is high, you could get a good income from the billboard.

Residential Properties close to heavy or noisy traffic should be discounted by 10 to 20 points throughout the transaction.

Bank initially approved my offer to buy a 6yo, modern, nice, heavy traffic, 8000sf foreclosed strip mall in Clayton County, GA for $475K cash.

Hey Max, I love this stuff so will share what I'm doing anytime.I bought a canned website and am running a small PPC campaign on Google and Bing to get traffic

They are usually only for traffic enforcement or vehicle accident type activities not responding to criminal activity.