I obviously can‘t give 10% of my profits.I’m curious what formula/standards others are using to calculate their charitable giving amounts.Thanks in advance for your input!

I would consider it one of my charitable givings for that year.. 

There is no sacrifice in doing #1 and not #2...the sacrifice comes when you do the opposite.We often talk about wanting more time with friends and family, or being more healthy, or more charitable, or having financial freedom, or whatever we say we want and then we make daily decisions that are completely disconnected from these goals. 

The best (IMHO)you can do is seek out a tax and wealth advisor that you can work with so they can better understand your long term preferences as it relates to your estate and then give you advice on sustainable income into retirement (passive and/or retirement accounts), charitable preferences and heirs, if applicable.

My wife and I started a non-profit charitable organization in 2017 in honor of our daughter who passed away from a congenital heart disease. 

Some business can absorb the cost of charitable donations and or good will.....

I've worked quite a bit with trusts - Charitable Remainders as well as Land Trusts. 

. + Religious, charitable, legal, educational, domestic, accounting services, architecture, engineering, surveying, and veterinary services. + Services rendered by nonprofit membership organizations for the promotion of the interest of the members. + Nonprofit educational and research agencies. + Public utilities as defined under Tenn.

we worked through the old owner and tried to get to the kids when ever possible.. all leads were leads until the logs were on the ground.. a few things we did to speed things up  were as posted above and pretty obviouswe set up 1031s  but hard to sell to an 80 year old who could not fathom how that could be legal.and a few did charitable remainder trusts  probably even more complicated and the ones' where we bought those deals I would say the sellers were pretty savvy folks not your typical tree farmer. so as many have stated whats the sellers best interest and your best interest is many times vis a vi taxation not aligned in any manner.

I expect my kids to remain well-grounded, manage our wealth well and use it for good.I may leave some wealth to a few responsible charitable organizations, but I'm certainly not interested in just handing out cash to the poor.