Also, consider who you’re hosting, is it families, business travelers, or medical professionals?

Single family homes are exempt from rent control when privately owned.  

Quote from @Eli Fazzo: @Will Gaston for how many investment properties can you use this 25% exemption? 

As for your neighbors, they could have exemptions like Homestead, widow, military disability and many others that can reduce the amount of taxes.

As a married couple, you can also take advantage of the $500k capital gain exemption.

Medical Payments: Provides coverage for an injury suffered on the premises.

You're feeding 2 dogs with one biscuit by taking care of your living expenses and generating rental income at the same time, and by living in the house and keeping it to 4, you generally get exemptions on things that might bother you to live with (IE you can choose whomever you want as your tenants without running afoul of fair housing laws).

Multifamily mindset has recruited students from all walks of life such as teachers, medical doctors, veterans, real estate agents, business men, and I was included into a group (multifamily mindset encourages students to form groups) and one of them is a veteran who is divorced, has kids to support, not employed during that time, got a loan of $40,000 for the tuition.

Lastly, if you’re currently taking a homestead exemption on property taxes, once that drops off (if you’re currently taking chose to transfer the exemption to your new home) your property taxes will likely increase $1k-$2k thus increasing your monthly mortgage.

I have worked with many medical professionals where they adopted the basic strategy you are trying to use.