Where are your current rental properties located?

Your 4 unit might be an investment to you, but to the bank it's your primary residence... and that's where the banks are going to have a hard time believing a couple that's married (and has a history of living together) are going both occupy two separate primary residences without getting separated or divorced...Obviously some exceptions here if you were located at seperate duty stations etc, but that's different.

Some locations you might lose money by renovating.

Its located on a long road where every house had been damaged by the storm.

People who rent vacation homes aren't going to start using the hotels and motels, they'll find vacation homes in other locations. 

(Well, it would be once the 6-plexes are fully rented.)Also consider what you have to maintain for each property:Office: 1 Roof6-plexes: 2 RoofsOffice: 4 HVAC units6-plexes: 12 furnaces + 12 AC window unitsOffice: 2 kitchenettes (Fridge, sink)6-plexes: 12 full kitchens (Above, plus range/oven, vent/hood, dishwasher, etc.)Office: 4 bathrooms6-plexes: 12 bathroomsA couple more confounding factors: The office building is built in 2005 and located in a suburb of a major metropolitan area currently experiencing substantial growth.

Would you care to give any advice on investing in the area (strategy, locating deals, financing, areas to avoid) 

Without knowing a remote location well or having a quality trusted team in place, I would be very hesitant to pull the trigger on a deal like this without having ALL of my facts straight and independently verified by multiple sources.Not trying to talk you out of it.  

The developers need both economies of scale and top-end rents to make the numbers work.Post some more details, location and your financial breakdown, and the community will help you walk through whether this is actually a viable plan. 

Since it is 2 Duplexes located on 2 different streets I would want to know the numbers for each individually.