Evictions take months here in DE so you could potentially lose out on 4 months rent or so and have to rehab the house. 

Prince Georges County MD loses a lawsuit on this about every 5 years or so because Pitbulls are illegal there.

Quote from @Arvand Sabetian: I think most others have already provided sound advice.I wanted to emphasis having a conversation with your tenants about the septic tank, not just a clause in the lease that you assume they'll read and understand.Many people are unaware of what they can be doing that causes issues to septic tanks (e.g., flushing the wrong items).Also, make sure you do a walkthrough yourself prior to filling the unit.

So, they lose the option fee, not the money down.FYI:  that's nothing new. 

Like "renting to section 8 tenants is actually really easy", "your agent is not on your team just connect with people like me doing hundreds of deals every day and use my team instead", that hood properties will have "15-25% net caps" for beginner out of state investors when in reality they will definitely lose money every month due to the rent not being enough $ to maintain a rental property, never mind all the tenant issues involved with this property class or the difficulty of managing them remotely... but he's done thousands of them just this week while sitting on the beach in Florida... 

Investors buy shares and earn returns through dividends and potential stock price appreciation.You typically can’t lose more than your initial investment with publicly traded REITs.

You will need to invest OOS unless you are ok with losing money for years.

You'll potentially increase your stress, fail to replace your lost income, and possibly lose part or all of your investment property equity.Focus on replacing your job and stabilizing your finances.

Some people hold it just because they won't make as much as they want, but then the market goes down and they lose more so you to know the sale and rental market as well as the trending nature of the area.

Your only real question here is how much additional equity can you earn before you sell before the rate resets and before you lose your capital gains exclusion, versus the opportunity costs if you sold and cashed out now.