@Yufei Liu Definitely need to check the zoning for the neighborhood.

I've considered driving for dollars but don't know how to target specific neighborhoods in my price range.

Also if I meet with a seller who calls me from my marketing and they have a perfectly nice home in a great neighborhood  the first thing I tell them is that they can get top dollar from the sale of their home with a realtor, and they most likely don't need to sell to me, because I will have to buy at a price where I can make money on the deal. 

However, I am priced out of all the nicer and desirable neighborhoods (Want to stay under 450K) . 

The property is located in Florida (In case that makes a difference) and does reside in an association area/neighborhood.

At the moment my wife and I are looking to purchase our first home (a fixer upper) in a nice neighborhood but the home has foundation issues such as leaning walls, cracked bricks, etc.

Don't buy in the roughest neighborhood in the urban core.

Option two: flip the OC house and take that cash to invest in a class B neighborhood.

What are everyone’s thoughts on  how businesses closing will impact the neighborhoods in your city?

Don't buy in the roughest neighborhood in the urban core.