What demographic areas are you comfortable with?

This is going to depend on your risk tolerance and preferences, but I'm happy to provide my input..If I were in your shoes, I'd do the HELOC because of your interest in BRRRR. if you were trying to do a long term rental, I would do a cash-out refi on your primary residence. 8 years is a long time to wait to do 1 deal, so I would personally shy away from depending solely on cash flow.

If you are comfortable with your new mortgage payment after you refi, I would totally do that. 

Your husband could then commute in relative comfort and use the commute time on the train for podcasts, reading, relaxing.

I’ve done quite a bit of research on BiggerPockets, youtube, podcasts, and still have a few remaining questions before I feel comfortable enough to take the plunge.1) Have you ever worked with a wholesaler directly?

Would love some advise from anyone who has been in my shoes, starting out on a new career in real estate and realistic short term goes as a new investor.

Can you make the cash out pay for itself and if the answer is a comfortable yes at those interest rates, then do it. 

If you are self-managing now and comfortable with the process of taking service calls, it won't be much different when you are out of state.

Here is an overview of the deal….100K View of THE DEAL:We own a multi-family lot valued at ~$45K We’ve completed a tri-plex design and current day construction cost is ~$373KI’ve studied and am comfortable with the economic outlook of the market we’re investing (e.g., population YoY growth, unemployment, median income growth, business anchors, etc.)

However, I know someone personally who had his loan called due so it's a gamble you have to be comfortable with.