If it needs foundation, the elevation variances are really what would impact your sewer lines, if this is a slab home.

Have you ever done an elevation certificate?

The historic main streets are filled with restaurants, outdoor cafes, shops, galleries, and other pedestrian friendly locations, mostly brick roads with pretty elevation changes. 

Within that list, you'll want to look at proximity to elevator and how close is that building to the pool, etc.

You can check the property on the FEMA flood maps https://msc.fema.gov/portal/search and determine the base flood elevation.

The existing half bath was lovingly referred to as the “murder bathroom”, You had to walk down a pitch black hallway, off the mechanical space, and the bathroom was elevated up about 8-10” (giving it maybe 6’-6” headroom) measured maybe 4' x 4' and the walls were made of laminate panels.

Some items to consider are accessible path of travel (gravel is not going to cut it), potential elevator, potential historical preservation involvement, and the biggest issue is if a business can garner enough clients to cover the cost and still make a living. 

You need to spend $10s of thousands if not $100s on drawings elevations civil engineers planners before you pay the plan submission fees to get in the door and they can say no or you need to make amendments that cost more $$$

@Angela Stevens The best thing to do is give the elevator pitch immediately when you talk to the broker.

@Cristian Aviles-Morales I don't really like sharing the nitty gritty but here's some short answers1. tenants moving in earlier than they should have caused occupational permit issues. work permits I didn't know I needed were required. some ahole competitor who lost the deal to me I'm pretty sure knocked down some electrical wiring to one of the buildings and mysteriously the day after an "anonymous" caller reported it to the city. some guy harassing my contractors while they were working which I'm pretty sure was the same guy who vandalized my wires.2. my elevator pitch to short term investors. would you rather generate .01% in a checking account or invest with me and get an annualized 8% back on your money. you're basically making 800 times more.