I did all of my loans with small local banks in my area and was always happy with the rates and service.

If you invest in a city with rapid and sustained appreciation, you can reinvest accumulated equity to buy additional properties using cash-out refinancing.

(note that there are seasoning periods with loans - shorter with DSCR loans, and longer with conventional. 

Joe its all about NPV  and rate of return for investors.. either way your going to take a pretty big hair cut out of your equity to do what your wondering about. 

Questions are what type of loan are you targeting?

@George Blower  Are you sure on the part that you can't take another 401k loan until 12 months after the first loan is repaid?  

I have high equity in my current duplex so planning on using that to fund down payment for the next property.  

At closing:The homeowner deeds the property to the straw borrower, relying on the false promises made by the ‘investor’All proceeds are used to pay off the defaulted loanThe homeowner walks away with nothingThe 'investor' pockets the equity and runsThe straw borrower defaults on the loanThe homeowner is evicted, loses the house and all equityThere are many variations of a foreclosure rescue scheme.

However, consider STR seasonality, local regulations, and management demands, and ensure your equity loan and new primary residence costs fit comfortably within your budget.

Freddie Mac only offers financing for single properties they do not offer 'Portfolio loans" meaning bundle them all into one loan.