I also work in the Rochester, NY area providing deals for cash buyers.

You might make it work if you can find a way to increase cash flow aside from the basic long term rental strategy. 

Purchase price: $295,000 Cash invested: $50,000 Single fam home, desirable neighborhood.

Quote from @Anshuman Thakur: Can someone please shed some light on how- convert 401k to SD IRA- how to use SDIRA to buy properties- how much down payment is typically required if we are using SDiRA to only fund downpayment on a multifamily CRE, and which banks typically work with SDIRAs- how does LLC structure- property management and cash flow work in this situation?

Cash flowing markets, low taxes, landlord friendly and large demand in renters. 

Quote from @Scott Cash: I'm part of a three-member LLC that owns a $10M commercial property outright (each holding 33.3%).

In my market - new build duplexes dont cash flow well but are typically a great 5-10 year investment. 

House hacking a duplex, even with negative cash flow upfront, is a great way to build equity while learning hands-on.

Cash flow will be a function of how much you put down. 

I would offer them cash for keys, or contact your attorney and start the eviction process if they decline.