If/when it comes up within tolerable levels for humans, it's on them now.3) If it comes up positive for dangerous mold: now you have a health hazard that would have gotten worse over time.

The original agent emails me to say the sellers have chosen not to move forward and I am in breach of contract.

Unfortunately, human nature is such that if I do spend hours, days, months vetting a sponsor, and ultimately sign off on them, I will already be biased to accepting the next deal they offer, regardless of whether it is good or not.  

Philadelphia happens to be better positioned than most to absorb life science assets because of the local human capital but look at all of the developments stalled or failing to break ground in University City because the developers can't obtain tenant commitments.

You can check out sites like Zillow or Redfin to see what houses are selling for and what rental prices look like in your chosen market. 

At the end of the day, we’re all humans and need each other.

Less risk.I considered long distance investing but instead have chosen to buy a few rentals in Spokane the last few years, I dont regret it.

If so I would push back, but if not, the appraiser really may have chosen the best comps for your property. 

Go to meetups, walk neighborhoods, visit properties, meet humans. 

I volunteer with the local Habitat for Humanity, Humane Society, and aim to help where I can.