Is there a way for the property owners to get those accounts transferred, or are they stuck with that real estate agent forever? 

I know a lot of people who do it, I would ask what is your exit. for example we have done it when we were doing some renovations and had a line of credit as well that we were going to transfer the cost too.

I was expecting these reservations to be transferred over to me upon closing.

@Kyle Steiner more than likely they will have you do an interspousal transfer.

@Denise Evans If the heirs have not taken action to move the title into an estate, or to transfer to an heir, how is the state supposed to know the person is deceased? 

If you plan on transferring the property into an LLC (which I agree with @Jonathan Klemm, is not always necessary or recommended) then you will have to register is with Indiana at inbiz.com if you did not form it in Indiana. 

I would rethink actually transferring the deed to a buyer if you are still on the hook for the note.

Now the trick with chase cards is to open a sapphire card(either work) and use them to transfer to Hyatt, or an international airline.

I'm curious about how they are able to convert your business credit cards into a cash line of credit while avoiding the high balance transfer interest rates.  

If it's possible still, it would be better for the grandmother to keep possession of the house and have the ownership transfer upon her death due to the step-up in basis the house would get.