Small city Rochester Minnesota, home of the prestigious Mayo Clinic plans to become global biotech hub/destination medical centre.  

I spent 5 years there with the Australian Trade Commission back in 70's.Because of the bad weather, pigeons & the ongoing IRA fireworks, we found it cheaper/safer to leave for 3 day weekends (flextime was great) for various Med destinations.

If your local market supports your approach and destination, jump on it.

Real estate is a people business, and you therefore seem unlikely to be destined for success.

It's not a destination.  

I have been to the Cayman Islands plenty of times, and love it, but I want to find somewhere else - a hidden gem maybe... that has yet to explode as a tourist destination, but close enough to a major town that airlines can fly into as I need to make it somewhat affordable and accessible to people who would like to rent it out.

Think of a goal as a destination and the map is the plan to get there.

It's liking picking the best road before deciding on the destination.

If you do not you are destined to fail.

The Mexican government then decided to create one of the biggest tourist destination in the world through massive public investment (through its Fonatur arm) and (foreign) private investment.