Quote from @Joe Norman:
As others have said, zoning rules and regulations are very local so it's hard to give general advice. Talk to someone at the government body that over sees zoning in your county/municipality. Go to them with specific questions about a specific property, listen, ask good questions, and be polite. You will need a relationship with them going forward.
While we likely can't answer any specific questions about your town's zoning, I am curious about what you are concerned about? Unless you're repurposing a property then the zoning doesn't matter too much (assumings its current use is a conforming one).
My concern is that my ideal property is a 4 bed 2 bath single family home. These are all in residential zones. However with living in a college town and house hacking, I will be renting out each room individually. With that said one of the main things I've seen is that no more than 2 unrelated people may live in the same house hold in a residential zone. so this holds me back to only being able to rent to one other person, leaving the other two bedrooms empty.