@Jorge Guerrero , it really depends on how the deal is structured to determine if the due on sale clause get triggered. I don't generally like to do lease options, but have structured a few. The way I have done it in the past is basically finding a tenant who is seriously interested in buying the house and renting it to them. Then I'll let them know that I'm interested in selling them the house at X price.
The rent will be set at higher than mortgage payments, then every year when I renew the rental contract to them, I will present them a purchase option with say 50% of the rent paid to date against the price of the house.
So each year they stay, the house gets cheaper and cheaper to purchase. Of course you need to work the numbers to figure out how many years you want to do this for, how much rent to set, what percent to give them back into the purchase price as each personal situation is very different.
My strategy in this case is to get out of a sticky situation with a win win for both sides and stop an asset from being cash flow negative, not to make more money. There are strategies to use lease options to make profit out of nothing, but it's too complicated and time consuming for me, so I only use this technique to get out of assets that don't conform to my investment target.