Yes, Syracuse is a diamond in the rough. Don't just buy cheap houses in the city, though. I would recommend going to the city and touring around so you know what you're getting into. There are some very rough parts. The old houses in the city need a lot of TLC. They all have lead paint, asbestos, and radon.
You could theoretically buy up one or two blocks of dilapidated houses near SU or Crouse Irving for cheap and fix them all at once and change the look of that particular block in the city, but it would be risky. Renting to SU students can be a complete nightmare because they can be heavy drinkers and destructive. There are serious students at SU and graduate students, but I don't know where they normal live...maybe out in the suburbs.
Some of the streets are less desirable because of the slope of the road/sidewalk and all the locals know you can't walk or drive on that street in the winter....something you don't know as a out of town investor.
There is also a culture of frugality overall. Don't think just because you're putting in nicer countertops and cabinets that renters or buyers will be willing to pay for that.
Overall the people in Syracuse are working class or lower middle class. There's isn't much as far as generational wealth. Houses did not increase in value that much over the last 20-30 years....and there's a reason for that. It's a depressed economy and you're not going to be able to get great rents. Making smaller apartments from single family isn't going to go over well either because people are used to getting more square footage for their money, unlike in NYC.
Micron is putting a chip factory in Clay, which is northeast of Syracuse. Probably won't be built for at least 10 years. It caused a surge in home and land prices in the Clay area. Overall the chip factory will promote a better economy but it may take time, maybe one or two decades.
There's a lot going for Syracuse, but tread carefully. There's an international airport. There's also Syracuse University and Upstate Medical Center. It's also smack dab in the middle of the state, so it's very central for conferences, shipping, and commuting. Even still, be careful.