I currently own a townhouse on the border of Midtown and Buckhead near Piedmont Hospital. I have been using the property as Airbnb for over a year now and aside from one reckless guest I haven't had any issues with them.
On average I get between $100-$300 cash flow a month but it varies due to events and time of year. For example, the Super Bowl was extremely lucrative, as well as the hotter months. But that gain is offset by the rest of the year when the average daily price is lower. I've found that daily price is heavily dependent on location and time of year. So to alleviate that, I was sure to purchase a property in a location that would always be in high to moderate demand. So far I've been right in that analysis, but I bought the property WITH the intention of using it as an AirBnB.
I think the two biggest factors you should consider are location and HOA. My HOA was an issue in the first few months because they felt I was violating our community guidance. I had to hire and attorney to arbitrate the issue on my behalf, but after that they let it go and I haven't had an issue since. Your HOA and its guidelines will be your biggest hurdle, so if you have not already purchased the property, you should be sure to review the guidelines thoroughly beforehand.
As far as location goes, keep in mind why and who is using AirBnB. Most, but not all, of my guests have been between 25-35 years old. The majority are coming for an event in the city and want to be close. You can get to most places with a $10 Uber from my place, and I know that is a big factor in the current success of the property. I would be wary of using a place too far out of the city for AirBnB.
I hope this was helpful.