@John Arendsen
I don't normally chime in on real estate topics as controversial as marijuana and real estate, but I do a very interesting background on this topic, as my family was formerly the landlord of a medical marijuana dispensary. Now each landlord's experience with this differs (much like every landlord's real estate experiences differ) but ours was a fairly positive experience.
At the time, we were struggling with vacancy issues, as our property is an older industrial property in a rougher part of town. The dispensary was also having issues finding a good location too: not only is there a stigma involved in being the landlord of anything marijuana-related, but here in the City of Oakland, dispensaries are limited in how and where they can operate. I recently spoke to a lawyer with some insight on this and he told me that dispensaries and grow houses (anything marijuana-related, for that matter) are heavily regulated by city and county laws. He told me that it's probably best to check with your local jurisdiction, as something as unrelated-sounding as zoning designation can have a significant impact on the legality of dispensaries and grow operations in a specific location (but it sounds like you already knew that, lol)
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Anyways, the laws in Oakland proved to be very favorable for dispensary landlords in that:
1) All dispensary patients not only had to have a license for their medicine, but their prescription could not be used within a 100-foot radius of the dispensary itself. This was extremely beneficial as we did not have to deal with any potential increased fire hazards or smells that come from smoking marijuana.
2) Because the dispensaries were only allowed to operate within a very specific area, (I have been told that their permit only allows them to operate within a few city blocks here in Oakland.) the dispensaries do their best to run a very smooth operation. Our former tenant kept their business immaculately clean and employed both an advanced security system as well as a traditional security guard. I have been told that because the business is still illegal in the eyes of the Federal government, many dispensaries and growing operations operate on a cash basis, hence the need for all the security. Despite the additional risk, the dispensary was an overall good tenant. They knew the stigma as well as the limitations associated with their business, so we, as landlords, were well compensated for taking on this type of tenant. The tenant always paid their rent on time and, although their busiest hours were in the evening, the dispensary took care of any and all of their own issues, without having to involve us. I suppose that our property's location in a primarily industrial neighborhood helped, as none of the neighbors seemed to really care about the nightly comings and goings.
3) Even though our dispensary tenant eventually moved out, our property was very adaptable and we were able to rent it to a true industrial tenant not long after the previous tenant vacated. Although this is my own opinion, I would think that it's pretty important for investors and landlords to consider other possible uses for a property. After all, it's impossible to predict the future and it could very well be the case that marijuana, even medical marijuana, remains a federally-illegal business for a while, so it's always best to have a backup in case things turn ugly.
Maybe one day marijuana will receive federal recognition for its medicinal purposes... or maybe not. But either way, we as landlords and potential landlords can't take on the risk of having any medical marijuana-related tenants without knowing all of our facts. I hope that helps, and good luck with your new venture!