@Steve Chan Every investment vehicle I utilize is tax advantaged. We invest through our 401k and get an employer match, we invest through an HSA and receive an employer contribution, we invest through a Roth IRA and we invest in mostly buy and hold RE. Notice how I said "through", you don't invest in a 401k/Roth/HSA, I invest in ETF's and index funds through those accounts. 401k and HSA decrease your current taxable income, Roth decreases your future taxable gains, and you should be aware of the numerous tax advantages of RE.
The point your trying to make of being in a higher tax bracket at retirement befuddles me. You should be positioning yourself to require almost no income to live once you're retired, your house is paid off, you're not investing into those multiple accounts, you have a fat HSA to cover medical expenses. You should have RE income and then you could subsidize with retirement accounts as necessary.
I'm going to diversify and I'm going to continue to invest in the stock market and in RE. So I'm going to take advantage of the tax benefits of what's offered to me. If you don't want to invest in the stock market, then no, you probably shouldn't worry about a 401k.