Well thought out response @Jay Hinrichs . All great points, there are some beautiful areas of CA. I lived in the Central Valley for a while a couple years ago and as a native New Englander was shocked when I moved there that not every part of CA is far left liberal; just in the major cities. To note, every major city in the country is blue, yes even Dallas and Houston.
Also @James Wise remember real estate is local and there are deals to be had in every market; even in a state where the population is declining like CA there can be great investment opportunities to scoop up. I usually scoff at real estate experts who just talk about national or regional macro trends. Every sub market moves on it's own trajectory. Heck sometimes it even comes down to block to block trends (think multi family in different school zones from one block to another). National/ regional/ state trends are certainly important, but knowing the local market and what investment strategy to use depending on what is happening is even more important.