Hi Brian!
As a property manager/agent in the Pocono Mountain area (PA), I would definitely recommend taking a look into this area for STR. There are some unique factors that set aside the Pocono areas from many others like the seasonal aspects of tourism. A Cool part of the Pocono mountains is that the tourist season lasts ALL year- not just for a few months out of the year. There are diverse activities year round from lake beaches, hiking, sightseeing, leaf changing tours, skiing, indoor waterpark resorts, outdoor parks, farms, zoos and historic areas.
As far as key factors to consider outside of location I would recommend 1. Look at a house that has unique factors. Think A-frames and chalets over the regular ranch stye homes. As a PM for a wide variety of units, the fun ones always outperform the cookie cutter. As far as other factors for an area to choose, outside of the location, I'd definitely say do your homework on the general feeling of STR by Township. Is the township taking any moves against/pro STR? Do they support it? Is the community welcoming of it? Lastly I'd say research the demographic of the parties that partake in tourism in the area. Are they mostly families? Couples? Big groups? Find a house that would appeal best to who you are selling to.
3. If you are located outside of the city it is located in, I'd definitely recommend a PM. Whether that looks like one subcontractor you trust, or a company who's brand identity you can get behind. Having boots on the ground with an STR can make or break the guest experience, as well as preventative maintenance and quality upkeep of your unit.
Good luck on your journey! STR is a fun one- you'll get to have some fun and get creative with your product. Enjoy it!