Hi Zachary,
I love your interest and careful thought on investing in real estate!
I am familiar with Portsmouth, Ohio and actually disagree with some of the other folks advice (no hard feelings to anyone) regarding investing there just because it is local. The asset return, in my opinion isn't there due to the location and lack of new businesses moving into the area. While the cost of entry is low and appealing, if the goal is to put your money to work my suggestion is to invest closer to where there are more jobs, so for the sake of your A-C, you should look closer to Columbus and/or Lexington.
Using the BRRRR method and 1031 tax deferment strategies are a great way to build your portfolio. I have built my personal investment property wealth doing both, and have been very successful (my bio has my full story). Part of the BRRRR method is leveraging asset appreciation, and again investing in areas with guaranteed returns (Columbus/Lexington) will help you get to the next investment property quicker.
In searching for a Realtor to represent you in a city you don't live, look for someone that has an established team that can assist you. In addition, make sure the Realtor is full time, and has experience with Investors, and a bonus if they have investment properties themselves.
You don't need 50+ properties to retire early, if you invest smartly. And investing smartly means if you want 50+ you can make that happen sooner and with better properties.
Keep making careful decisions and utilizing resources such as BiggerPockets!
All the best,
Andrea