Massachusetts cost of building house

[A Cavalli]

Hi. I have been speaking with builders and been getting a big range of quotes from $175 to $450 per square foot. On this forum I have read that prices depend based on location. Could someone explain why there would a huge difference in price per Sq ft between say Natick vs Wellesley or weston vs Waltham in the absense of permitting fee. I can understand higher cost for remote locations.