Rent to a person with one large pet

[Travis Hargreaves]

Hey everyone I have a quick question. I am renting out a single family home on a corner lot with 0.4 acres. A tenant meets all of my minimum qualifications, except a large pet. She has a "Great Pyrenees, 90 lbs, 6 years old, house trained, and very friendly." She states he is a nice dog, but that is bigger than what I was hoping for. The neighbor does run an in house day care. So would this dog be to big and make it a deal breaker or you have had luck in these situations. Please let me know what you think. Thank you for your time.