Larger Apartment buildings Vs 4plexes/duplexes.

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I have been researching like crazy for the possibility of investing in larger apartment buildings but seem to analyze myself back to smaller multi units and duplexes every time. The loans are better and easier for the under 4 unit buildings, The cash flow seems better, and then the inventory seems better for these as well. I also picture the target millenial population to be more interested in smaller units as well. Does anyone have any insight on this topic?