A mix of commercial and residential topics is fine. 

I have heard mixed responses on whether to charge both first and last month’s rent and a security deposit, or just first or last month’s rent and security deposit.

HOWEVER, I'm reading a lot of mixed reviews on whether I'll be able to put the property in an Ohio LLC (we won't be the primary owners of the LLC, since it will be owned by the Holding LLC.

No - "DSCR Loans" are for residential investment properties only (with only a very minor exception for small mixed use properties that are majority residential in nature in every way)

If mixed in with your deposits and reserve funds, you may accidentally spend money you shouldn't have.

Purchase price: $250,000 Cash invested: $50,000 Mixed use building in Brooklyn that my family has owned for more than 25 years.

Stores that have since moved-in to the space include Costco, HomeGoods, Petco, Hobby Lobby, Dick’s Sporting Goods, Field and Stream, Best Buy, and Ashley Furniture Home Store.Transit Oriented/Mix-Use Developments- Mobile Bay Bridge Project is said to begin in 2020, costing $2.1 billion and consisting of a six-lane cable stay bridge over the Mobile Bay connecting Mobile and Eastern Shore.

How much of the S8 rent is covered by the program and how much is the tenant's responsibility is dependent on how much money the tenant makes.The housing department has a formula they use to determine the voucher mix.

I’ve had some good insight from this forum with mixed responses which help reinforce that neither is a specially bad option. 

I own several SFH, duplexes, triplexes, and a quad but I'm in discussion regarding a 13 unit mixed use property that is of interest to me mostly due to location (I own several properties in the area and it's near me and I have a good pulse on the town).