The answer to this will come down to comfort level, funds available, and strategy you are looking to implement. 

I do not lend in NC so I cannot help but I have several options with 20% down on a 2-4 unit.

If you have 1-4 unit residential that's already cash flowing I would go DSCR if you have a ratio of 1 or more.

I have 0 experience ground up construction loan program nationwide that does NOT require GC to sign anything, only provide proof of 3 C/O's (certificate of occupancy) over the last year I.e. built received occupancy permission now unit is on market or habitable. 700+ FICO I can get you 80%LTC loan to cost on the project on ground up construction for 1-4 units.

What if you have an apartment complex with 20 units?

In the multi unit buildings I put on lease "Each tenant shares responsibility for removing snow and salting on both walkways and sidewalk infront of property" and I have them initial before we execute lease.

I currently have my investment portfolio all in North Jersey and planning on purchasing a number of units in Syracuse.

With a budget of $300K-$400K, you could potentially find single-family homes or small multi-units in those areas.I'd recommend researching rental demand near universities like Duke or NC State or even checking out neighborhoods with strong job growth near tech hubs.

I have two duplex units and am subdividing into townhomes for higher market value.

. $150 cash flow on any rental especially a triplex is dangerzone imo. 1 month of vacancy of 1 unit could destroy a years worth of financial gains.