@Ellie PerlmanI think one key factor is opportunity zone benefits as well

Appreciation factor is another consideration.  

The other big factor is the intention of the end-buyer.

I have given this idea some thought and would love to try it out but I think one major factor is making sure the landlord is comfortable and feels confident enough to trust you, the AirBnB host, will pay the rent and take care of the unit.

How much you let your lender (soft, hard, medium, whatever) make on this deal should not be your deciding factor. I

You also have the vacancy factor. I

The construction should be of more consistent quality given it is repeatably produced in a controlled factory environment.

Especially if you're considering buying out of town/state.Another factor is what's the trend in your area regarding lead paint and asbestos mitigation?

Imagine a 6200 seat amphitheater surrounded by Yamashiro's only location outside of Hollywood, Sugar Factory, Poppy Rose and host of other restaurant's. 

The numbers work, but I dont have that kind of cash to start-out.As such, as far as markets, I look for small cities and suburbs of bigger cities where I can find some combo diverse businesses with large offices or factories and/or contain or are near to a couple colleges or universities.